Curcumin

Jianfeng Chemical

Specifications

HS Code	648187
Chemical Name	diferuloylmethane
Appearance	yellow - orange crystalline powder
Solubility	poorly soluble in water, soluble in organic solvents like ethanol and acetone
Source	derived from the rhizomes of Curcuma longa (turmeric plant)
Antioxidant Property	high antioxidant capacity, scavenges free radicals
Anti Inflammatory	modulates inflammatory pathways
Potential Anticancer	may inhibit cancer cell growth and induce apoptosis
Anti Microbial	shows antibacterial, antifungal properties
Neuroprotective	may protect neurons from damage, potentially beneficial for neurodegenerative diseases
Liver Protective	helps in protecting liver cells from damage
Coloring Property	used as a natural food coloring agent

Packing & Storage

Packing	10 - gram sachet packaging for Curcumin chemical.
Storage	Curcumin should be stored in a cool, dry place, away from direct sunlight. It is best kept in a tightly - sealed container to prevent moisture absorption and oxidation. Temperatures around 2 - 8°C are ideal for long - term storage in a refrigerator if possible. Avoid storing near strong odors as curcumin can absorb them.
Shipping	Curcumin, a chemical, is shipped in sealed, air -tight containers. These are carefully packed to prevent any spills or degradation. Shipping adheres to safety regulations for handling chemicals, ensuring secure transit.

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General Information

Historical Development

Curcumin is the source of the essential agent of turmeric. The use of turmeric has been around since ancient times. In the past, dating back to ancient texts, there were many records of its use as medicine. In the field of traditional medicine, it is often valued by physicians.
At the beginning, it was mostly used to regulate qi and blood, treat abdominal diseases, and relieve pain. After years, with the deepening of medical inquiry, the cognition of curcumin has also increased. Since the beginning of the records of Materia Medica, after generations of medical practice, its utility has become more and more clear.
Today, modern scientific intervention has made the study of curcumin more subtle. Not only its chemical structure has been clarified, but also its potential in antioxidant, anti-inflammatory and other aspects has been explored. From the ancient traditional medicinal use to the present scientific research, the development of curcumin is clear, and it may be even more promising in the future.

Product Overview

Curcumin is derived from the natural ingredient of turmeric, which has been valued by the Fang family for a long time. Its color is golden and mild in nature. Looking at its effectiveness, it has antioxidant properties, can clear free radicals in the body, and slow down cell decay. And it has anti-inflammatory effects and is beneficial to all kinds of inflammation.
It is widely used in the field of health. It can protect the heart and veins, stabilize its work, and reduce cardiovascular disease; or it can benefit the brain, help the mind and refresh the mind, and prevent the birth of brain diseases.
The method of preparation, through extraction and purification of various techniques, obtains this essence. The quality is pure and the utility is quite good. However, when using it, it is necessary to follow the medical principles and follow the quantity in order to obtain its good results and protect the well-being of the body.

Physical & Chemical Properties

Curcumin, which belongs to the extract of turmeric, has unique physical and chemical properties. Its color is golden, fresh and bright, like autumn chrysanthemum blooming. In terms of solubility, it is difficult to dissolve in water, but easily soluble in organic solvents such as alcohols, just like a flood dragon diving, hidden in a suitable place.
Its chemical structure is exquisite, containing a conjugated double bond system, like strings connected, resonant resonance. This structure endows it with extraordinary stability and activity. And its melting point is specific, just like the principle that individuals adhere to.
From the perspective of physical properties, it is finely powdery and delicate to the touch, just like quicksand passing through the finger. In the light and heat environment, its properties change subtly, or the color is slightly changed, or the activity is slightly changed, just like the wise man changes with the times. This is also a manifestation of the unique physical and chemical properties of Curcumin.

Technical Specifications & Labeling

Curcumin is a delicate substance. Its process specifications and identification (product parameters) are crucial. As far as process specifications are concerned, high-quality turmeric needs to be selected from raw materials to ensure its purity. The extraction method should follow a precise process, temperature control and time limit to ensure the purity and activity of Curcumin.
As for the identification (product parameters), its content must be clear, if not lower than a certain proportion, to prove its quality. The appearance and color should also be clear, with a bright yellow color. Solubility and other characteristics should also be described in detail so that the user can understand. In this way, the essentials of Curcumin product process specifications and identification (product parameters) can be obtained to pass on its effect and benefit everyone.

Preparation Method

Curcumin is an important component of turmeric, and its preparation method is crucial.
The raw materials are selected, and the high-quality turmeric is based on high-quality turmeric, which needs to be pure in color, positive taste and free of impurities. After fine grinding, it becomes a fine powder to increase the reaction contact area.
In the production process, ethanol is used as the solvent and miscible with turmeric powder in an appropriate proportion. At a specific temperature, gently stir to promote its full reaction. After filtration, the insoluble substance is removed. The filtrate is distilled under reduced pressure, and the ethanol is recycled and reused to obtain a concentrate.
During the reaction steps, the temperature is strictly controlled, and the temperature fluctuations cause the purity of the product and the yield to change. The duration is also critical. If the reaction is too short, the reaction is incomplete,
In the purification mechanism, the concentrate is purified by column chromatography. Fillers are selected to separate Curcumin from impurities. After crystallization treatment, high-purity Curcumin crystals are obtained, which meet product Quality Standards.

Chemical Reactions & Modifications

Curcumin, the pigment extracted from plant turmeric, has attracted much attention in the field of chemistry, and its chemical reaction and modification are particularly important for researchers.
Looking at its chemical reaction, Curcumin has the structure of phenolic hydroxyl and α, β-unsaturated β-diketone, so it can react with nucleophiles and electrophiles. In case of alkali, its phenolic hydroxyl can be deprotonated, causing molecular charge distribution to change, which often affects its solubility and stability. In addition, its unsaturated structure is prone to electrophilic addition, such as hydrogen halide addition, which can obtain products with different structures.
Talking about modification, it aims to expand its application. After chemical modification, its stability, solubility and biological activity can be increased. If the phenolic hydroxyl group is modified by esterification method, it can improve its fat solubility, and it is easier to penetrate the biofilm in the drug delivery system to achieve the purpose of synergy.
The chemical reaction and modification research of Curcumin paves the way for its wide use in the fields of medicine, food and materials. Those who are waiting for research will work hard to explore more potential.

Synonyms & Product Names

Curcumin is an important ingredient extracted from turmeric, also known as curcumin. In the classics of Materia Medica, although it is not named Curcumin, there are many examples related to it.
When viewing turmeric, it is warm in nature and hard in taste. In traditional medicine, it is often used to promote blood circulation, circulate qi, pass menstruation and relieve pain. Curcumin also has many wonderful effects. Modern research shows that it has anti-inflammatory, antioxidant and other properties.
In ancient classics, although there is no direct name of Curcumin, it is not uncommon to use turmeric as a medicine. For example, to treat the disease of blood stasis and block, turmeric can be combined with other medicines to regulate the unsmooth flow of qi and blood. Curcumin, this ingredient, may be the key to turmeric's medicinal effect. Although there are different names in ancient and modern times, they are all for helping people with illness and protecting health.

Safety & Operational Standards

"Curcumin Product Safety and Operation Specifications"
Curcumin is a miraculous substance that is becoming more and more important in today's research. To understand the safety and operation specifications of Curcumin products is really the important task of our researchers.
At the safe end, check the source of its raw materials for the first time. Use natural materials, choose a clean place, and avoid pollution. If it is synthesized artificially, the process must follow strict regulations, and the reagents used must be non-toxic and harmless. After the finished product, its purity and impurities must be carefully checked. Impurities exceed the standard, or cause adverse effects, endangering the health of the user.
In terms of operating specifications, when preparing, the environment must be clean, and the temperature and humidity should also be precisely controlled. Different processes have different requirements for conditions. During the grinding process, the force should be uniform, and the particle size should be suitable. When mixing, stir moderately to ensure that the ingredients are uniform.
When storing, it should be placed in a dry and cool place, protected from light and moisture. The packaging should also be tight to prevent it from coming into contact with air and moisture.
When using this product, it is essential to grasp the quantity. Excessive use of it may cause adverse reactions. And if the user has a special body, such as allergic properties, we must be cautious.
We are researchers of Curcumin products, and we should strictly abide by safety and operating practices, so that this miraculous thing can benefit human beings without the risk of harm. In this way, it will live up to our original intention of research.

Application Area

Curcumin has strengths in various application fields. In the field of medicine, it has anti-inflammatory and antioxidant properties, or can help heal injuries and slow down various inflammatory diseases. In the world of diet, it can be used as a natural colorant and flavor agent to increase the color and flavor of food, and has a health effect. Furthermore, in the road of beauty, because of its antioxidant properties, it can protect the skin, slow its aging, and maintain the luster and elasticity of the skin. Curcumin has shown its unique effects in many application fields such as medicine, diet, and beauty. It is valued by everyone, and the future development is also worth looking forward to.

Research & Development

In recent years, I have learned a lot from the research of Curcumin. Curcumin, which is derived from the ingredient of turmeric, has been valued by the Fang family for a long time.
I have studied the classics carefully, collected the opinions of many people, and explored its nature with scientific methods. After repeated experiments, I know that it is good for human health and has many benefits. It may be antioxidant and slow down the decline of the body; or it can be anti-inflammatory and help heal various diseases.
However, if we want to promote its use in the public, we still need to work hard. We should deeply study its principles and widely study its use, so that this treasure can be used by the world. Over time, the effect of Curcumin will be revealed in the world, benefit all living beings, and promote the prosperity of its industry. It is my generation's wish.

Toxicity Research

Observing Curcumin's product, the world often regards it as a wonderful thing, but the study of its toxicity cannot be ignored. Ancient researchers have many omissions, and they have not detailed the depth of its poison. Now we observe its toxicity with a rigorous state. After various experiments, observe its impact on the living being, the change of cells, and the shape of organs. Although it has all kinds of benefits, it is also poisonous in high quantities. Or disturb the order of cells, or damage the ability of organs. Although it cannot be discarded because of its toxicity, it must be carefully studied, and its safe amount should be carefully examined, so that this product can be used to its full effect without hurting people. The study of toxicity is related to the health of people's livelihood, and it must not be meticulous.

Future Prospects

There are Curcumin things today, but their nature is very different, and they are quite promising in the field of medicine. Looking at the medicine of ancient times, every time I seek new things to cure diseases, Curcumin may be the hope of those who come.
Its power in health and healing diseases has gradually emerged after various studies. It may be able to control diseases before they start, or it can be cured. And its origin is natural, its sex is peaceful, and there is no major harm.
Although the current understanding is not complete, those who study it are all eager. Looking forward to the future, I will detail its nature, make good use of its capabilities, and apply it to everyone, so that everyone can be healthy. Let this natural treasure shine brightly on the road of medicine, become a healthy reliance for the future, and prolong the life of the world. This is a promising vision.

Frequently Asked Questions

What are the main effects of Curcumin?

Curcumin is derived from the natural pigment of turmeric, which has attracted attention since ancient times for its function in health and healing diseases.
Curcumin has excellent antioxidant properties. It can resist the damage of free radicals in the body, slow down cell aging, and protect body tissues and organs. Like the strong shield of a city, it protects cells from oxidative stress and maintains their normal function. Although the name of curcumin is not directly stated in the "Compendium of Materia Medica", the effect of turmeric "breaking blood and promoting qi, passing menstruation and relieving pain" may be related to curcumin's antioxidant and maintaining qi and blood.
Anti-inflammatory is also an important function of curcumin. It can inhibit the generation and release of inflammatory mediators, and is helpful in the treatment of chronic inflammatory diseases, such as arthritis. Ancient physicians used turmeric as medicine in case of carbuncle inflammation, or because of the anti-inflammatory properties of curcumin. It is like a good general in the army, calming the chaos of inflammation and restoring the body's peace.
Furthermore, curcumin is beneficial to the digestive system. It can promote bile secretion, help food digestion, and protect the stomach and intestinal mucosa. Gu Yun "The spleen and stomach are the foundation of the acquired day". Curcumin helps the digestion of the spleen and stomach, like fertile soil in the field, nourishing the vitality of the viscera.
In addition, curcumin may have the function of nourishing the nervous system. It can slow down the process of neurodegenerative diseases and help cognitive function. Although ancient books do not describe this in detail, its antioxidant and anti-inflammatory properties may be indirectly beneficial to nerve health, such as quiet mountains and forests, nourishing the nerves.
Curcumin has many functions in health care and disease, and is actually a good medicine for natural feeding. It will be widely used in today's deep research.

Curcumin may play a role in the treatment of diseases

Curcumin is derived from the natural component of turmeric, which may be effective in the healing of many diseases. Looking at the medical canon of the past and the research of the present, curcumin may be beneficial in the following types of diseases.
First, inflammation-related diseases. "On the Origin and Syndrome of All Diseases" says: "Those with inflammation are the signs of stagnant qi and blood, and endogenous heat." Curcumin has anti-inflammatory properties and can regulate inflammatory mediators in the body. If rheumatism and arthralgia, joint redness, swelling, heat and pain, and poor qi and blood, curcumin may help it relieve inflammation and make qi and blood smooth.
Second, it is related to diseases of the digestive system. " "On the Spleen and Stomach" says: "Those with the spleen and stomach are the officials of the warehouse, and the five flavors come out." Curcumin may protect the spleen and stomach and promote digestion. For example, in those with epigastric distension and indigestion, curcumin may increase gastrointestinal motility, help transport water and valleys, and make the spleen and stomach healthy.
Third, in diseases of the nervous system. "Lingchu Meridians" says: "People are born, and they first become sperm, and then the brain is born." Curcumin has antioxidant power, or can protect nerve cells, slow down the transformation of nerve degeneration, such as preventing Alzheimer's disease, helping the essence of the brain to be maintained, and making the gods smart.
Fourth, the prevention and treatment of cancer. Although there is no name of "cancer" in ancient times, there are records of similar symptoms. Curcumin may inhibit the proliferation of cancer cells and induce their apoptosis, in order to achieve anti-cancer power, such as for some cancers, it may reduce its potential and help heal.
However, it needs to be made clear that although curcumin has many potential effects, when treating diseases, it should be based on individual differences, in line with the dialectical treatment method of traditional medicine, supplemented by the accurate diagnosis of modern medicine, in order to maximize its length and achieve good results.

How safe is Curcumin?

Curcumin is derived from the natural pigment of turmeric, and its safety has attracted much attention. According to ancient books, turmeric is taken for a long time to lighten the body and improve qi, and curcumin may also be beneficial. Looking at modern studies, one is that under normal intake doses, no obvious toxicity has been found. Many experiments have taken animals as subjects, and different doses of curcumin have been administered, mostly showing good tolerance. Second, human clinical trials have also shown that most people can adapt to moderate intake of curcumin, and there are few serious adverse reactions.
However, it should also be noted that if excessive intake, there may be discomfort. Such as some individuals or gastrointestinal reactions, such as nausea, diarrhea, etc. Due to individual differences, the tolerance to curcumin is different. And curcumin is complex in metabolism in the body. Although it is safe, it may interact with other medicines when taken together.
In summary, normal consumption of curcumin-containing foods or appropriate supplementation of curcumin supplements is usually quite safe. However, for health reasons, it is especially necessary to consult a doctor before ingestion to prevent accidents.

What is the optimal dose of Curcumin?

Curcumin is a natural pigment, and it also has many health care properties. However, the optimal dosage is still inconclusive, because individual differences are quite large, and many factors are affected.
Looking at people's physique, those who are strong or have strong tolerance, the appropriate dose may be higher than those who are weak. And the state of the disease is different. If it is a mild recuperation, the dose can be slightly lighter; if it is a serious illness, the increment needs to be considered. And the difference in age is also an important reason. Children's organs are delicate and the dose should be light; the qi and blood of the elderly are gradually declining, and they also need to be moderately controlled.
According to ancient books, there is no precise quantification. However, there are many studies today. Daily health care, or take hundreds of milligrams per day, about 300-600 milligrams, divided into two to three times, in order to slow down the effect of long-term work. If used for auxiliary treatment of diseases, such as inflammation, or can be increased to 1000-2000 mg per day, then this dose should be used under medical supervision.
When taking curcumin, you should also pay attention. Because it is difficult to dissolve in water, it can be taken with lipids to increase absorption, such as cooking with a little oil. And long-term high doses may have adverse reactions, such as gastrointestinal discomfort. Therefore, for the best dosage, according to personal circumstances, follow the advice of the doctor, and do not act without authorization to obtain the benefits of curcumin and avoid its harm.

How is Curcumin metabolized in the body?

Curcumin is metabolized in the body. Although there is no detailed description in ancient books, it can be explored in today's scientific view.
When curcumin is taken orally into the body, it is not easy to absorb because of its low water solubility through the gastrointestinal tract. If it is not absorbed, it may come out with the feces. And if it is absorbed, it enters the liver first. In the liver, curcumin can be converted into corresponding conjugates by the action of various enzymes, such as glucuronation and sulfuration. The polarity of this conjugate increases, which is conducive to excretion.
In addition, curcumin may also undergo structural changes under the action of intestinal microorganisms. The intestinal flora can decompose curcumin into small molecule products, some of which may have different physiological activities, and are easier for the human body to absorb and utilize.
After being metabolized by the liver, curcumin and its metabolites will be partially excreted into the intestines with bile, and part of this process may be reabsorbed, which is the so-called hepatointestinal circulation. Ultimately, the metabolites are excreted through urine and feces to maintain balance in the body.
In summary, the metabolic pathway of curcumin in the body is complex. It completes the metabolic journey in the body through a series of processes such as liver transformation, intestinal flora action, and hepatointestinal circulation.